The GIMAP5 Polyclonal Antibody (CAB8684) is a valuable tool for researchers studying the GIMAP5 protein, a member of the GTPase family that plays a role in immune cell function. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.GIMAP5 is involved in regulating T cell survival and proliferation, making it a key player in the immune response. Research on GIMAP5 is particularly important in the context of autoimmune diseases, where aberrant immune cell function can lead to harmful immune responses. By targeting the GIMAP5 protein, researchers can gain insight into the mechanisms of autoimmune diseases and potentially develop targeted therapies.
This polyclonal antibody binds specifically to the GIMAP5 protein, allowing for precise detection and analysis in a variety of cell types. Its high reactivity and specificity make it an ideal tool for immunology research and investigations into immune cell function. By using the GIMAP5 Polyclonal Antibody, researchers can further our understanding of immune cell regulation and potentially uncover new therapeutic targets for immune-related diseases.
Product Name:
GIMAP5 Rabbit Polyclonal Antibody
SKU:
CAB8684
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 190-270 of human GIMAP5 (NP_060854.2).
Sequence:
WGSV EEQR QQQA ELLA VIER LGRE REGS FHSN DLFL DAQL LQRT GAGA CQED YRQY QAKV EWQV EKHK QELR ENES NWAY K
Lysosome, Mitochondrion outer membrane, Single-pass type IV membrane protein.
Calculated MW:
35kDa
Observed MW:
34kDa
This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene encodes an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between this gene and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene.
Purification Method:
Affinity purification
Gene ID:
55340
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GIMAP5 Rabbit pAb (CAB8684) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
