The GIGYF2 Polyclonal Antibody (CAB12069) is a valuable tool for researchers studying GIGYF2, a protein involved in protein translation and mRNA stability regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is optimized for Western blot applications. By specifically targeting the GIGYF2 protein, researchers can accurately detect and analyze its expression levels in various cell types, making it an ideal choice for studies in molecular biology and cell biology.GIGYF2, also known as GRB10 Interacting GYF Protein 2, plays a crucial role in the regulation of gene expression and cellular processes. Its involvement in mRNA metabolism and post-transcriptional control makes it a promising target for research into mechanisms underlying various diseases, including cancer and neurological disorders.
Understanding the function of GIGYF2 can provide insights into potential therapeutic strategies aimed at targeting this protein for the treatment of certain diseases.Overall, the GIGYF2 Polyclonal Antibody (CAB12069) offers researchers a reliable tool for investigating the role of GIGYF2 in cellular pathways and disease mechanisms, ultimately contributing to the advancement of scientific knowledge and the development of potential therapeutic interventions.
Product Name:
GIGYF2 Rabbit Polyclonal Antibody
SKU:
CAB12069
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 350-500 of human GIGYF2 (NP_001096617.1).
This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in this gene were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
26058
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GIGYF2 Rabbit pAb (CAB12069) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
