The GHSR Polyclonal Antibody (CAB1840) is a vital tool for researchers studying the growth hormone secretagogue receptor (GHSR), a key player in the regulation of growth hormone secretion and energy homeostasis. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the GHSR protein, researchers can easily detect and analyze its expression in various cell types, making it an ideal choice for studies in endocrinology and metabolism research.
GHSR, also known as the ghrelin receptor, is involved in the control of appetite, food intake, and energy balance. Dysregulation of GHSR signaling has been linked to metabolic disorders such as obesity and diabetes, highlighting the importance of studying this receptor in the context of these conditions. By gaining a deeper understanding of GHSR function, researchers can potentially identify new therapeutic targets for the treatment of metabolic diseases and improve overall patient outcomes.
Product Name:
GHSR Rabbit Polyclonal Antibody
SKU:
CAB1840
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GHSR (NP_940799.1).
This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.
Purification Method:
Affinity purification
Gene ID:
2693
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from rat brain, using GHSR Rabbit pAb (CAB1840) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
