The GHRHR Polyclonal Antibody (CAB8421) is a valuable tool for researchers studying Growth Hormone Releasing Hormone Receptor (GHRHR), a key player in regulating growth hormone release and various physiological processes. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for Western blot applications.GHRHR is a crucial component of the growth hormone axis, playing a pivotal role in growth, metabolism, and other biological functions. Dysregulation of GHRHR signaling has been linked to growth disorders, metabolic disorders, and other health conditions, making it an attractive target for therapeutic intervention.
By utilizing the GHRHR Polyclonal Antibody, researchers can effectively detect and analyze GHRHR expression in different cell types, shedding light on its role in various biological processes. This antibody is an essential tool for studies exploring the molecular mechanisms underlying growth hormone regulation and its implications for health and disease.
Product Name:
GHRHR Rabbit Polyclonal Antibody
SKU:
CAB8421
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human GHRHR (NP_000814.2).
This gene encodes a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in this gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature.
Purification Method:
Affinity purification
Gene ID:
2692
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using GHRHR Rabbit pAb (CAB8421) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
