GHITM Antibody (PACO41062)
- SKU:
- PACO41062
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
GHITM Antibody (PACO41062)
The Ghitm Polyclonal Antibody (PAC041062) offered by AssayGenie is a key tool for researchers studying the Ghitm protein, a crucial player in immune regulation pathways. This rabbit-raised antibody is highly specific to human samples and has been rigorously validated for Western blot applications. By binding to the Ghitm protein, this antibody enables precise detection and analysis across various cell types, making it a valuable asset for studies in immunology and cancer research.Ghitm, also known as an immune regulatory molecule, plays a pivotal role in maintaining immune balance by inhibiting immune responses.
Its involvement in immune response modulation positions it as a promising target for research related to cancer, autoimmune diseases, and chronic inflammatory conditions. By unraveling the mechanisms of Ghitm activity, researchers can gain insights that pave the way for the development of innovative therapies aimed at leveraging or controlling immune function in disease contexts.
| Antibody Name: | GHITM Antibody (PACO41062) |
| Antibody SKU: | PACO41062 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:500 |
| Species Reactivity: | Human, Rat |
| Immunogen: | Recombinant Human Growth hormone-inducible transmembrane protein (293-345AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: Rat brain tissue. All lanes: GHITM antibody at 2.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 38 kDa. Observed band size: 38 kDa. |
 | IHC image of PACO41062 diluted at 1:400 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | IHC image of PACO41062 diluted at 1:400 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c. |
| Synonyms: | Growth hormone-inducible transmembrane protein (Dermal papilla-derived protein 2) (Mitochondrial morphology and cristae structure 1) (MICS1) (Transmembrane BAX inhibitor motif-containing protein 5), GHITM, DERP2 MICS1 TMBIM5 |
| UniProt Protein Function: | GHITM: Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c. Belongs to the BI1 family. |
| UniProt Protein Details: | Protein type:Mitochondrial; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 10q23.1 Cellular Component: integral to membrane; mitochondrial inner membrane Molecular Function:protein binding Biological Process: apoptosis |
| UniProt Code: | Q9H3K2 |
| NCBI GenInfo Identifier: | 15213977 |
| NCBI Gene ID: | 27069 |
| NCBI Accession: | Q9H3K2.2 |
| UniProt Secondary Accession: | Q9H3K2,O95894, Q5VT95, Q9H0P2, A8K9Z9, D3DWE0, |
| UniProt Related Accession: | Q9H3K2 |
| Molecular Weight: | 37,205 Da |
| NCBI Full Name: | Growth hormone-inducible transmembrane protein |
| NCBI Synonym Full Names: | growth hormone inducible transmembrane protein |
| NCBI Official Symbol: | GHITMÂ Â |
| NCBI Official Synonym Symbols: | DERP2; MICS1; My021; PTD010; TMBIM5; HSPC282Â Â |
| NCBI Protein Information: | growth hormone-inducible transmembrane protein |
| UniProt Protein Name: | Growth hormone-inducible transmembrane protein |
| UniProt Synonym Protein Names: | Dermal papilla-derived protein 2; Mitochondrial morphology and cristae structure 1; MICS1; Transmembrane BAX inhibitor motif-containing protein 5 |
| Protein Family: | Growth hormone-inducible transmembrane protein |
| UniProt Gene Name: | GHITMÂ Â |
| UniProt Entry Name: | GHITM_HUMAN |
| Antibodies | ELISA Kits |
| GHITM Antibody (PACO03879) | Human MICS1 / GHITM ELISA Kit |
| GHITM Antibody (PACO09463) | Human GHITM (Growth Hormone Inducible Transmembrane Protein) CLIA Kit (HUES01060) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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