The GHIâ„¢ Anti-CD300A Antibody (PACO22352) is a polyclonal antibody specifically designed for research involving CD300A, a cell surface molecule known for its immune regulatory functions. This antibody, produced through rabbit immunization, exhibits high reactivity with human samples and has been validated for Western blot applications. By binding to the CD300A protein, researchers can effectively detect and analyze its expression in various cell types, making it an excellent tool for studies in immunology and cancer research.CD300A, also referred to as an immune inhibitory receptor, plays a crucial role in immune homeostasis by regulating inflammatory responses and inhibiting allergic reactions.
Its involvement in immune response modulation makes it a promising target for research on diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. A comprehensive understanding of CD300A's activity is essential for the development of potential therapies that could either harness or modulate immune function in these disease contexts.In summary, the GHIâ„¢ Anti-CD300A Antibody (PACO22352) offers researchers a reliable tool for investigating the role of CD300A in immune regulation and disease pathogenesis, ultimately contributing to advancements in therapeutic strategies for various immune-related conditions.
Antibody Name:
GHITM Antibody (PACO22352)
Antibody SKU:
PACO22352
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human GHITM.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from LOVO cells, using GHITM antibody.
Background:
Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c.
Synonyms:
derp2; dkfzp566c0746; flj26584; ghitm; growth hormone inducible transmembrane protein
UniProt Protein Function:
GHITM: Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c. Belongs to the BI1 family.
UniProt Protein Details:
Protein type:Mitochondrial; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 10q23.1
Cellular Component: integral to membrane; mitochondrial inner membrane
