The Ghitm Antibody (PACO16688) is a polyclonal antibody designed for research involving Ghitm, a protein involved in immune regulation. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications such as Western blot. It specifically binds to the Ghitm protein, allowing for detection and analysis in different cell types.Ghitm, also known as an immune regulator, plays a crucial role in immune response modulation by inhibiting immune responses.
Understanding the function of Ghitm is essential for research in immunology and cancer studies. Its involvement in immune regulation makes it a potential target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. This antibody is ideal for researchers looking to study immune function and its modulation in different disease contexts.
Antibody Name:
GHITM Antibody (PACO16688)
Antibody SKU:
PACO16688
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Fusion protein of human GHITM
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO16688(GHITM Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200).
Background:
Growth hormone-inducible transmembrane protein is a protein that in humans is encoded by the GHITM gene. Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c.
Synonyms:
growth hormone inducible transmembrane protein
UniProt Protein Function:
GHITM: Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c. Belongs to the BI1 family.
UniProt Protein Details:
Protein type:Mitochondrial; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 10q23.1
Cellular Component: integral to membrane; mitochondrial inner membrane
