The Ghitm Polyclonal Antibody (PACO16687) is a valuable tool for researchers studying Ghitm, a protein involved in immune regulation and inflammation. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the Ghitm protein, this antibody enables accurate detection and analysis in various cell types, making it an ideal choice for studies in immunology, inflammation, and related fields.Ghitm, also known as an immune modulator, plays a crucial role in regulating immune responses and maintaining immune homeostasis. Its involvement in inflammation and immune function makes it a promising target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
Understanding the role of Ghitm is essential for developing novel therapies that can modulate immune responses and potentially treat various immune-related disorders.Overall, the Ghitm Polyclonal Antibody is a reliable tool for researchers interested in investigating the functions of Ghitm and its implications in immune regulation and inflammatory processes. Its high reactivity and specificity make it a valuable asset for studies aimed at uncovering the roles of Ghitm in health and disease.
Antibody Name:
GHITM Antibody (PACO16687)
Antibody SKU:
PACO16687
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Fusion protein of human GHITM
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO16687(GHITM Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200).
Background:
Growth hormone-inducible transmembrane protein is a protein that in humans is encoded by the GHITM gene. Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c.
Synonyms:
growth hormone inducible transmembrane protein
UniProt Protein Function:
GHITM: Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c. Belongs to the BI1 family.
UniProt Protein Details:
Protein type:Mitochondrial; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 10q23.1
Cellular Component: integral to membrane; mitochondrial inner membrane
