GHITM Antibody (PACO09463)
- SKU:
- PACO09463
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
GHITM Antibody (PACO09463)
The GITM Antibody (PAC009463) is a polyclonal antibody specifically designed for research related to GITM, a protein associated with immune regulation and immune response modulation. Raised in rabbits, this antibody is highly reactive with human samples and is validated for Western blot applications. By binding to the GITM protein, researchers can detect and analyze its presence in various cell types, making it an ideal tool for studies in immunology and cancer research.GITM, also known as immune inhibitory receptor, plays a vital role in immune homeostasis by regulating inflammation and inhibiting allergic reactions.
Its involvement in immune response modulation makes it a valuable target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of GITM is essential for the development of therapies that can either enhance or modulate immune function in these disease contexts.Overall, the GITM Antibody (PAC009463) offers researchers a reliable tool for investigating the role of GITM in immune regulation and disease pathology, providing valuable insights for potential therapeutic interventions.
| Antibody Name: | GHITM Antibody (PACO09463) |
| Antibody SKU: | PACO09463 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human GHITM |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | growth hormone inducible transmembrane protein;GHITM;DERP2;DKFZp566C0746;FLJ26584;HSPC282;MICS1;My021;PTD010;TMBIM5 ; |
| UniProt Protein Function: | GHITM: Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c. Belongs to the BI1 family. |
| UniProt Protein Details: | Protein type:Mitochondrial; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 10q23.1 Cellular Component: integral to membrane; mitochondrial inner membrane Molecular Function:protein binding Biological Process: apoptosis |
| UniProt Code: | Q9H3K2 |
| NCBI GenInfo Identifier: | 15213977 |
| NCBI Gene ID: | 27069 |
| NCBI Accession: | Q9H3K2.2 |
| UniProt Secondary Accession: | Q9H3K2,O95894, Q5VT95, Q9H0P2, A8K9Z9, D3DWE0, |
| UniProt Related Accession: | Q9H3K2 |
| Molecular Weight: | 37,205 Da |
| NCBI Full Name: | Growth hormone-inducible transmembrane protein |
| NCBI Synonym Full Names: | growth hormone inducible transmembrane protein |
| NCBI Official Symbol: | GHITMÂ Â |
| NCBI Official Synonym Symbols: | DERP2; MICS1; My021; PTD010; TMBIM5; HSPC282Â Â |
| NCBI Protein Information: | growth hormone-inducible transmembrane protein |
| UniProt Protein Name: | Growth hormone-inducible transmembrane protein |
| UniProt Synonym Protein Names: | Dermal papilla-derived protein 2; Mitochondrial morphology and cristae structure 1; MICS1; Transmembrane BAX inhibitor motif-containing protein 5 |
| Protein Family: | Growth hormone-inducible transmembrane protein |
| UniProt Gene Name: | GHITMÂ Â |
| UniProt Entry Name: | GHITM_HUMAN |
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