The GH Polyclonal Antibody (PACO34150) is a high-quality antibody designed for research involving GH, a growth hormone that regulates growth, metabolism, and overall body composition. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in various applications, including Western blotting.GH plays a crucial role in various physiological processes, including promoting growth and development, regulating metabolism, and influencing immune function. Research involving GH is essential for understanding its role in conditions such as growth disorders, metabolic diseases, and hormone-related cancers.
The GH Polyclonal Antibody binds specifically to the GH protein, allowing for accurate detection and analysis in various cell types. Its high reactivity and specificity make it an ideal tool for studies in endocrinology, growth disorders, and cancer research. By studying GH and its effects, researchers can gain valuable insights into its mechanisms of action and potential therapeutic applications in related diseases.
Antibody Name:
gH Antibody (PACO34150)
Antibody SKU:
PACO34150
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human cytomegalovirus
Immunogen:
Recombinant Human cytomegalovirus Envelope glycoprotein H protein (24-195AA)
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis (By similarity). In human cytomegalovirus, forms two distincts complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope. The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA. The gH-gL-UL128-UL130-UL131A pentamer is essential for viral entry in epithelial, endothelial and myeloid cells via interaction with host NRP2 (By similarity).
Synonyms:
Envelope glycoprotein H (gH), gH, UL75
UniProt Protein Function:
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis.
