The GGTLC1 Polyclonal Antibody (PAC026961) is a valuable tool for researchers studying the GGTLC1 protein, which is involved in various cellular functions, including metabolism and cancer progression. This antibody, produced in rabbits, exhibits strong reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the GGTLC1 protein, this antibody enables researchers to detect and analyze GGTLC1 expression in different cell types, making it an ideal choice for studies in molecular biology and cancer research.GGTLC1, also known as gamma-glutamyltransferase-like protein 1, plays a crucial role in regulating glutathione metabolism and cellular redox balance.
Dysregulation of GGTLC1 has been implicated in various diseases, including cancer and metabolic disorders. Therefore, understanding the function and expression of GGTLC1 is essential for developing targeted therapies and diagnostic tools for these conditions.Overall, the GGTLC1 Polyclonal Antibody (PAC026961) offers researchers a reliable tool for investigating the role of GGTLC1 in cellular processes and disease states, ultimately contributing to advancements in the fields of oncology and metabolic research.
Antibody Name:
GGTLC1 Antibody (PACO26961)
Antibody SKU:
PACO26961
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Glutathione hydrolase light chain 1 protein (1-225AA)
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO26961 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human pancreatic cancer using PACO26961 at dilution of 1:100.
Background:
anchored component of external side of plasma membrane, gamma-glutamyltransferase activity, glutathione metabolic process, leukotriene biosynthetic process
This gene encodes a member of the gamma-glutamyl transpeptidase (GGT) family, which are important in the metabolism of glutathione. The most ubiquitously expressed human GGT gene, GGT1, encodes a single transmembrane polypeptide that is post-translationally processed to form a heavy and a light chain. In contrast, the product of this gene only contains homology to the light chain region, and lacks a transmembrane domain. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2008]
