The GGH Polyclonal Antibody (CAB5464) is a valuable tool for researchers studying GGH, an enzyme involved in folate metabolism and cellular proliferation. This polyclonal antibody, generated in rabbits, offers high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the GGH protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in cancer biology, pharmacology, and drug development.GGH plays a crucial role in folate metabolism, which is essential for DNA synthesis and repair, making it a key target in cancer research.
Dysregulation of GGH has been linked to various cancers and understanding its function is valuable for developing targeted therapies. Additionally, GGH inhibitors have shown promise as potential treatments for certain cancer types.By utilizing the GGH Polyclonal Antibody (CAB5464), researchers can gain valuable insights into the role of GGH in cancer development and progression, facilitating the development of novel treatment strategies. Its high specificity and sensitivity make it a reliable tool for studying GGH expression and activity in various experimental settings.
Product Name:
GGH Rabbit Polyclonal Antibody
SKU:
CAB5464
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-230 of human GGH (NP_003869.1).
This gene catalyzes the hydrolysis of folylpoly-gamma-glutamates and antifolylpoly-gamma-glutamates by the removal of gamma-linked polyglutamates and glutamate.
Purification Method:
Affinity purification
Gene ID:
8836
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GGH antibody (CAB5464) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
