GGA2 Rabbit Polyclonal Antibody (CAB1186)
- SKU:
- CAB1186
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | GGA2 Rabbit Polyclonal Antibody |
SKU: | CAB1186 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GGA2 (NP_055859.1). |
Sequence: | MAAT AVAA AVAG TESA QGPP GPAA SLEL WLNK ATDP SMSE QDWS AIQN FCEQ VNTD PNGP THAP WLLA HKIQ SPQE KEAL YALT VLEM CMNH CGEK FHSE VAKF RFLN ELIK VLSP KYLG SWAT GKVK GRVI EILF SWTV WFPE DIKI RDAY QMLK KQGI IKQD PKLP VDKI LPPP SPWP KSSI FDAD EEKS KLLT RLLK SNHP EDLQ AANR LIKN LVKE EQEK SEKV SKRV SAVE EVRS HVKV LQEM LSMY RRPG QAPP DQEA LQVV YERC EKLR PTLF RLAS DTTD DDDA LAEI LQAN |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | VEAR; GGA2 |
Positive Sample: | HepG2,Raji,MCF7,THP-1,22Rv1,Mouse brain,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Endosome membrane, Golgi apparatus, Peripheral membrane protein, trans-Golgi network membrane. |
Calculated MW: | 67kDa |
Observed MW: | 72-80kDa |
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly.
Purification Method: | Affinity purification |
Gene ID: | 23062 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |