The GGA2 Polyclonal Antibody (CAB1186) is a valuable tool for researchers studying the Golgi-associated, gamma-adaptin ear containing, ARF binding protein 2 (GGA2). This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications to detect the GGA2 protein.GGA2 is a crucial component of intracellular trafficking pathways, playing a key role in sorting proteins within the Golgi complex and transporting them to their correct destinations within the cell.
Dysregulation of GGA2 has been implicated in various diseases, making it a promising target for therapeutic interventions.By using the GGA2 Polyclonal Antibody, researchers can accurately detect and analyze GGA2 expression in different cell types, shedding light on its function in cellular processes. This antibody is an essential tool for studies in cell biology, molecular biology, and disease research, facilitating insights into the intricate mechanisms of intracellular protein trafficking and potential therapeutic targets.
Product Name:
GGA2 Rabbit Polyclonal Antibody
SKU:
CAB1186
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GGA2 (NP_055859.1).
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly.
Purification Method:
Affinity purification
Gene ID:
23062
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GGA2 antibody (CAB1186) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
