The GFRAL Antibody (HRP Conjugated) is a high-quality research tool designed for the detection of GFRAL, a receptor protein involved in energy regulation and appetite control. This antibody, raised and conjugated in rabbits, demonstrates high specificity and sensitivity for human samples, making it an ideal choice for various research applications.GFRAL, also known as glial cell line-derived neurotrophic factor receptor alpha-like, plays a crucial role in mediating the effects of the hormone GDF15 on body weight regulation and energy balance.
By targeting GFRAL with this antibody, researchers can explore its function in metabolic disorders, obesity, and related conditions. Validated for use in Western blotting and other immunoassay techniques, this antibody provides researchers with a reliable tool for studying GFRAL expression and signaling pathways. With its potential applications in metabolic research and drug development, the GFRAL Antibody (HRP Conjugated) offers valuable insights into the role of GFRAL in physiological and pathological processes.
Antibody Name:
GFRAL Antibody, HRP conjugated (PACO36907)
Antibody SKU:
PACO36907
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human GDNF family receptor alpha-like protein (19-351AA)
Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways.
Synonyms:
GDNF family receptor alpha-like, GFRAL, C6orf144
UniProt Protein Function:
GFRAL: Belongs to the GDNFR family.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 6p12.1Cellular Component: integral to membrane; intracellular; plasma membraneBiological Process: negative regulation of neuron apoptosis; stress-activated protein kinase signaling pathway
