The GFRAL Antibody FITC Conjugated (PAC036908) is a high-quality antibody designed for research involving GFRAL, a cell surface receptor that plays a key role in regulating energy metabolism. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it an ideal tool for studying the function and expression of GFRAL in various cell types.GFRAL, also known as glial cell line-derived neurotrophic factor receptor alpha-like, is involved in mediating the effects of the hormone GDF15, which helps regulate food intake and energy balance.
This makes GFRAL a potential target for research into metabolic disorders, obesity, and other related conditions.The FITC conjugation of this antibody allows for easy visualization and detection of GFRAL in cells using fluorescence microscopy and flow cytometry techniques. Its high specificity and sensitivity make it a valuable tool for researchers studying the role of GFRAL in metabolism and metabolic disorders.
Antibody Name:
GFRAL Antibody, FITC conjugated (PACO36908)
Antibody SKU:
PACO36908
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human GDNF family receptor alpha-like protein (19-351AA)
Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways.
Synonyms:
GDNF family receptor alpha-like, GFRAL, C6orf144
UniProt Protein Function:
GFRAL: Belongs to the GDNFR family.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 6p12.1Cellular Component: integral to membrane; intracellular; plasma membraneBiological Process: negative regulation of neuron apoptosis; stress-activated protein kinase signaling pathway
