The GFRA3 Polyclonal Antibody (CAB2955) is a valuable tool for researchers studying the GFRA3 protein, a crucial component in the nervous system. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. It specifically binds to GFRA3, enabling precise detection and analysis in various cell types.GFRA3 is a receptor for the glial cell line-derived neurotrophic factor (GDNF) family ligands, playing a key role in neuronal development and survival. Its involvement in neural function makes it a target of interest in neurobiology and neurodegenerative disease research.
Understanding the functions and pathways involving GFRA3 could provide insights into potential therapeutic interventions for conditions such as Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders.By utilizing the GFRA3 Polyclonal Antibody, researchers can further explore the mechanisms and roles of GFRA3 in neural development and degeneration, ultimately advancing our understanding of the nervous system and potentially facilitating the development of novel treatments for neurological disorders.
Product Name:
GFRA3 Rabbit Polyclonal Antibody
SKU:
CAB2955
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 32-240 of human GFRA3 (NP_001487.2).
The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin.
Purification Method:
Affinity purification
Gene ID:
2676
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GFRA3 Rabbit pAb (CAB2955) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
