GFRA2 Rabbit Polyclonal Antibody (CAB2954)
- SKU:
- CAB2954
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | GFRA2 Rabbit Polyclonal Antibody |
SKU: | CAB2954 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 360-464 of human GFRA2 (NP_001486.4). |
Sequence: | DVNV SPKG PSFQ ATQA PRVE KTPS LPDD LSDS TSLG TSVI TTCT SVQE QGLK ANNS KELS MCFT ELTT NIIP GSNK VIKP NSGP SRAR PSAA LTVL SVLM LKLA L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | NTNRA; RETL2; TRNR2; GDNFRB; NRTNR-ALPHA; GFRA2 |
Positive Sample: | U-87MG,LO2,HepG2,HeLa,Mouse lung,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, GPI-anchor, Lipid-anchor. |
Calculated MW: | 52kDa |
Observed MW: | 34kDa/55kDa |
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 2675 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |