The GFPT2 Polyclonal Antibody (CAB15374) is a valuable tool for researchers studying GFPT2, an enzyme involved in the biosynthesis of amino sugar precursors for protein glycosylation. This antibody, produced in rabbits, demonstrates high reactivity to human samples and has been validated for use in Western blot applications. By specifically binding to the GFPT2 protein, this antibody enables the detection and analysis of GFPT2 in various cell types, making it ideal for research in biochemistry and glycobiology.GFPT2 plays a crucial role in the regulation of protein glycosylation, a post-translational modification essential for proper protein folding and function.
Dysregulation of protein glycosylation has been implicated in various diseases, including cancer and metabolic disorders. Therefore, studying GFPT2 and its enzymatic activity is important for understanding the mechanisms underlying these pathologies and developing targeted therapies.Overall, the GFPT2 Polyclonal Antibody offers researchers a powerful tool for investigating the role of GFPT2 in protein glycosylation pathways and its potential implications in disease. Its specificity and reactivity make it an essential component of studies aimed at unraveling the complexities of protein glycosylation and its impact on cellular processes.
Product Name:
GFPT2 Rabbit Polyclonal Antibody
SKU:
CAB15374
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 200-260 of human GFPT2 (NP_005101.1).
Predicted to enable glutamine-fructose-6-phosphate transaminase (isomerizing) activity. Predicted to be involved in UDP-N-acetylglucosamine metabolic process; fructose 6-phosphate metabolic process; and protein N-linked glycosylation. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in cytosol. Implicated in type 2 diabetes mellitus.
Purification Method:
Affinity purification
Gene ID:
9945
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GFPT2 antibody (CAB15374) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
