The GFPT1 Polyclonal Antibody (CAB3882) is a valuable tool for research involving GFPT1, a key enzyme involved in the regulation of glucose metabolism and the hexosamine biosynthetic pathway. This antibody, produced in rabbits, has high specificity and sensitivity for detecting GFPT1 in human samples, making it ideal for use in Western blotting applications.GFPT1 plays a crucial role in the production of UDP-GlcNAc, a vital precursor for the synthesis of glycoproteins, proteoglycans, and glycolipids. Dysregulation of GFPT1 has been implicated in various diseases, including cancer, diabetes, and neurodegenerative disorders.
By targeting GFPT1, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic strategies.By utilizing the GFPT1 Polyclonal Antibody, researchers can effectively study the expression levels and localization of GFPT1 in different cell types and tissues, providing valuable information for further understanding the role of this enzyme in health and disease. This antibody is a valuable asset for studies in biochemistry, molecular biology, and drug discovery efforts targeting GFPT1-related pathways.
Product Name:
GFPT1 Rabbit Polyclonal Antibody
SKU:
CAB3882
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human GFPT1 (NP_002047.2).
This gene encodes the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway. The product of this gene catalyzes the formation of glucosamine 6-phosphate.
Purification Method:
Affinity purification
Gene ID:
2673
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using GFPT1 antibody (CAB3882) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
![Mouse Gfpt1 (Glutamine-fructose-6-phosphate aminotransferase [isomerizing] 1) ELISA Kit](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/218244/575619/mouse-gfpt1-glutamine-fructose-6-phosphate-aminotransferase-isomerizing-1-elisa-kit__00483.1698846461.jpg?c=2 "Mouse Gfpt1 (Glutamine-fructose-6-phosphate aminotransferase [isomerizing] 1) ELISA Kit")
![Mouse Gfpt1 (Glutamine-fructose-6-phosphate aminotransferase [isomerizing] 1) ELISA Kit](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/218244/598339/mouse-gfpt1-glutamine-fructose-6-phosphate-aminotransferase-isomerizing-1-elisa-kit__30126.1703612285.jpg?c=2 "Mouse Gfpt1 (Glutamine-fructose-6-phosphate aminotransferase [isomerizing] 1) ELISA Kit")
![Rat Gfpt1 (Glutamine-fructose-6-phosphate aminotransferase [isomerizing] 1) ELISA Kit](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/218413/574310/rat-gfpt1-glutamine-fructose-6-phosphate-aminotransferase-isomerizing-1-elisa-kit__72813.1698759109.jpg?c=2 "Rat Gfpt1 (Glutamine-fructose-6-phosphate aminotransferase [isomerizing] 1) ELISA Kit")
![Rat Gfpt1 (Glutamine-fructose-6-phosphate aminotransferase [isomerizing] 1) ELISA Kit](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/218413/596363/rat-gfpt1-glutamine-fructose-6-phosphate-aminotransferase-isomerizing-1-elisa-kit__86182.1703606046.jpg?c=2 "Rat Gfpt1 (Glutamine-fructose-6-phosphate aminotransferase [isomerizing] 1) ELISA Kit")