The GFM1 Polyclonal Antibody (CAB5077) is a valuable tool for researchers studying GFM1, a protein involved in mitochondrial translation and protein synthesis. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the GFM1 protein, this antibody enables researchers to detect and analyze GFM1 levels in various cell types, making it an essential component for studies in cell biology and mitochondrial function.GFM1 is a critical player in mitochondrial ribosome biogenesis and protein synthesis, making it a key target for research in mitochondrial disorders, neurodegenerative diseases, and cancer.
Understanding the role of GFM1 in cellular function and disease pathogenesis is important for developing potential therapeutic interventions targeting mitochondrial dysfunction.Overall, the GFM1 Polyclonal Antibody (CAB5077) is a reliable tool for researchers investigating the role of GFM1 in cellular processes and disease pathophysiology. Its specificity and sensitivity make it a valuable asset for studies aiming to uncover the molecular mechanisms underlying mitochondrial translation and protein synthesis.
Product Name:
GFM1 Rabbit Polyclonal Antibody
SKU:
CAB5077
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 482-751 of human GFM1 (NP_079272.4).
Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known.
Purification Method:
Affinity purification
Gene ID:
85476
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using GFM1 Rabbit pAb (CAB5077) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 45s.
