The GFER Polyclonal Antibody (CAB5463) is a powerful research tool designed for studying GFER, a protein involved in cellular metabolism and oxidative stress response. This antibody, produced in rabbits, exhibits high specificity and sensitivity for GFER in human samples, making it ideal for Western blotting and immunofluorescence applications.GFER, also known as Growth Factor, ERV1 Homolog (S. cerevisiae), is a key player in maintaining cellular redox balance and protecting cells from oxidative damage. Research indicates that dysregulation of GFER is associated with various diseases, including cancer, neurodegenerative disorders, and metabolic syndromes.
Therefore, investigating GFER expression and function is crucial for understanding the underlying mechanisms of these conditions and potentially identifying therapeutic targets.By utilizing the GFER Polyclonal Antibody (CAB5463), researchers can accurately detect and quantify GFER levels in different cell types and tissues, allowing for detailed analysis of its role in cellular processes. This antibody provides valuable insights into the function of GFER, paving the way for innovative research in fields such as cancer biology, neurobiology, and metabolic diseases.
Product Name:
GFER Rabbit Polyclonal Antibody
SKU:
CAB5463
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 81-205 of human GFER (NP_005253.3).
The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene.
Purification Method:
Affinity purification
Gene ID:
2671
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using GFER Rabbit pAb (CAB5463) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
