The GFAP Rabbit Monoclonal Antibody (CAB19058) is specifically designed for research involving glial fibrillary acidic protein (GFAP), a crucial protein found in astrocytes in the central nervous system. Astrocytes play a significant role in supporting neuronal function and maintaining the blood-brain barrier, making GFAP a valuable marker for studying neuroinflammation, brain injury, and neurodegenerative diseases.This antibody, generated in rabbits, demonstrates high reactivity with human samples and is validated for use in various applications, including immunohistochemistry and immunofluorescence.
By binding specifically to GFAP, researchers can accurately detect and analyze the distribution and expression levels of GFAP in different brain regions and pathological conditions.Overall, the GFAP Rabbit Monoclonal Antibody (CAB19058) is an essential tool for investigating the role of GFAP in neurological disorders and advancing our understanding of astrocyte function in the central nervous system. Its reliability and specificity make it a valuable asset for both basic research and clinical studies aimed at developing new therapies for neurodegenerative conditions.
Product Name:
GFAP Rabbit Monoclonal Antibody
SKU:
CAB19058
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GFAP (P14136).
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method:
Affinity purification
Gene ID:
2670
Clone Number:
ARC0206
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GFAP antibody (CAB19058) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
