The GFAP Polyclonal Antibody (PAC051538) is a valuable tool for researchers studying Glial Fibrillary Acidic Protein (GFAP), a key marker of astrocytes in the central nervous system. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting human GFAP protein in Western blot applications.GFAP is a filament protein that plays a crucial role in maintaining the structure and function of astrocytes, the most abundant cell type in the brain and spinal cord. Abnormal expression or mutations in GFAP are associated with various neurological disorders, including glioblastoma, Alzheimer's disease, and multiple sclerosis.
By targeting GFAP with this antibody, researchers can investigate the role of astrocytes in these diseases and explore potential therapeutic strategies.With its reliable performance and broad applicability in neuroscience and brain research, the GFAP Polyclonal Antibody (PAC051538) is a valuable asset for scientists seeking to unravel the complexities of astrocyte biology and its implications for neurological health and disease.
Antibody Name:
Gfap Antibody (PACO51538)
Antibody SKU:
PACO51538
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Rat, Mouse
Immunogen:
Recombinant Rat Glial fibrillary acid, c protein (1-430AA)
Western Blot. Positive WB detected in: Mouse brain tissue, Rat brain tissue. All lanes: Gfap antibody at 2.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 50, 49 kDa. Observed band size: 50 kDa..
Background:
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
Synonyms:
Glial fibrillary acid, c protein (GFAP), Gfap
UniProt Protein Function:
Function: GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
NCBI Summary:
intermediate filament protein specific for astrocytes [RGD, Feb 2006]
