The GET4 Polyclonal Antibody (CAB16190) is a powerful tool for researchers studying the protein GET4 in cellular processes. GET4, also known as TRC35, is involved in the targeting and insertion of tail-anchored membrane proteins into the endoplasmic reticulum membrane. This polyclonal antibody, produced in rabbits, exhibits high specificity and reactivity with human samples, making it ideal for Western blot applications.By targeting the GET4 protein, researchers can gain valuable insights into the mechanisms underlying protein targeting and membrane insertion in cells. This antibody is essential for studying the role of GET4 in various cellular processes, including protein translocation and membrane biogenesis.
Its versatility and reliability make it a valuable tool for research in cell biology, molecular biology, and protein targeting pathways.Overall, the GET4 Polyclonal Antibody (CAB16190) is a crucial asset for researchers exploring the complex interplay of proteins involved in membrane biogenesis and protein targeting within cells. Its high specificity and reactivity make it an invaluable tool for advancing our understanding of cellular processes and identifying potential therapeutic targets for a range of diseases.
Product Name:
GET4 Rabbit Polyclonal Antibody
SKU:
CAB16190
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-327 of human GET4 (NP_057033.2).
Enables chaperone binding activity. Involved in cytoplasmic sequestering of protein; maintenance of unfolded protein involved in ERAD pathway; and tail-anchored membrane protein insertion into ER membrane. Located in chromosome; cytosol; and nuclear lumen. Part of BAT3 complex.
Purification Method:
Affinity purification
Gene ID:
51608
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GET4 Rabbit pAb (CAB16190) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
