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Gephyrin Rabbit Monoclonal Antibody (CAB4729)

SKU:
CAB4729
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
GEPH
GPH
GPHRYN
HKPX1
MOCODC
Research Area:
Metabolism
  • Metabolism Antibodies 3 Anti-Gephyrin Antibody CAB4729
  • Metabolism Antibodies 3 Anti-Gephyrin Antibody CAB4729
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Gephyrin Rabbit Monoclonal Antibody
SKU:CAB4729
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Gephyrin (NP_001019389).
Sequence:MATE GMIL TNHD HQIR VGVL TVSD SCFR NLAE DRSG INLK DLVQ DPSL LGGT ISAY KIVP DEIE EIKE TLID WCDE KELN LILT TGGT GFAP RDVT PEAT
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:GPH; GEPH; HKPX1; GPHRYN; MOCODC; Gephyrin
Positive Sample:293T,Hep G2,Mouse liver,Rat liver
Conjugate:Unconjugated
Cellular Localization:Cell junction, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, cytoskeleton, postsynaptic cell membrane, synapse
Calculated MW:80kDa/83kDa
Observed MW:93kDa

This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known.

Purification Method:Affinity purification
Gene ID:10243
Clone Number:ARC1109
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using Gephyrin Rabbit mAb (CAB4729) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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