Gephyrin Rabbit Polyclonal Antibody (CAB8572)
- SKU:
- CAB8572
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- IF
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | Gephyrin Rabbit Polyclonal Antibody |
SKU: | CAB8572 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 520-769 of human Gephyrin (NP_065857.1). |
Sequence: | TVGV TEVE VNKF PVVA VMST GNEL LNPE DDLL PGKI RDSN RSTL LATI QEHG YPTI NLGI VGDN PDDL LNAL NEGI SRAD VIIT SGGV SMGE KDYL KQVL DIDL HAQI HFGR VFMK PGLP TTFA TLDI DGVR KIIF ALPG NPVS AVVT CNLF VVPA LRKM QGIL DPRP TIIK ARLS CDVK LDPR PEYH RCIL TWHH QEPL PWAQ STGN QMSS RLMS MRSA NGLL MLPP KTEQ YVEL HKGE VVDV MVIG RL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | GPH; GEPH; HKPX1; GPHRYN; MOCODC; Gephyrin |
Positive Sample: | 293T,Mouse brain,Mouse liver,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, cytoskeleton, postsynaptic cell membrane, synapse. |
Calculated MW: | 80kDa |
Observed MW: | 103kDa |
This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known.
Purification Method: | Affinity purification |
Gene ID: | 10243 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |