The GenieFluor Violet 450 Anti-Mouse TCR Antibody (H57-597/HB218) is a powerful tool for researchers studying T cell receptor (TCR) expression in mouse models. This antibody, designed for use in flow cytometry applications, is specifically targeted towards the TCR complex, allowing for precise detection and analysis of TCR-positive cell populations. With its high specificity and sensitivity, this antibody enables researchers to investigate T cell activation, differentiation, and function in various experimental settings.The TCR plays a fundamental role in the adaptive immune response by recognizing antigens presented on the surface of antigen-presenting cells. The ability to accurately detect and quantify TCR expression is essential for understanding immune responses in health and disease, including infectious diseases, autoimmunity, and cancer.
The GenieFluor Violet 450 Anti-Mouse TCR Antibody (H57-597/HB218) provides researchers with a reliable tool to explore T cell biology and uncover insights into immune system function.Overall, this antibody is a valuable asset for immunologists, cancer researchers, and anyone investigating T cell-mediated immune responses in mouse models. Its exceptional performance and application-specific design make it an essential component in advancing our understanding of T cell biology and its implications in various disease contexts.
Genie Fluor Violet 450 Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
Genie FluorViolet 450
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Gene ID:
21577
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR-β is a member of the immunoglobulin superfamily and a component of the CD3/TCR complex (along with TCR-α). It is expressed on α/β TCR-bearing T cells and thymocytes. The CD3/TCR complex plays a key role in antigen recognition, signal transduction, and T cell activation.