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GenieFluor Violet 450 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114] (AGEL2942)

SKU:
AGEL2942
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2b, κ
Clone:
M5/114
Conjugation:
AFViolet 450
€149
Frequently bought together:

Description

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GenieFluor Violet 450 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]

The GenieFluor Violet 450 Anti-Mouse MHC II (I-A/I-E) Antibody (M5/114) is a high-quality antibody designed for research in immunology and related fields. This antibody, specifically targeting the MHC class II proteins I-A and I-E in mice, is essential for studying antigen presentation and immune responses in murine models.By utilizing this antibody, researchers can accurately detect and analyze MHC II expression in mouse samples, enabling a better understanding of the immune system's response to various stimuli. The M5/114 antibody is validated for use in various applications, including flow cytometry, immunohistochemistry, and immunofluorescence, providing flexibility for different experimental setups.

MHC class II molecules play a crucial role in presenting antigens to CD4+ T cells, initiating adaptive immune responses. By targeting these molecules with the M5/114 antibody, researchers can delve deeper into the mechanisms of immune recognition and regulation in mouse models. This antibody's high specificity and sensitivity make it an invaluable tool for investigations into autoimmune diseases, infectious diseases, and immunotherapy research.Overall, the GenieFluor Violet 450 Anti-Mouse MHC II (I-A/I-E) Antibody (M5/114) offers researchers a reliable and effective means to study MHC class II proteins in mouse models, advancing our understanding of immune responses and immune-mediated diseases.

Product Title:GenieFluor Violet 450 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]
SKU:AGEL2942
Size:50 Tests, 100 Tests, 200 Tests
Clone No:M5/114
Synonyms:H2-Ab1/Eb1;Major histocompatibility protein class II beta chain;MHC class II H2-IA-beta-psi;I-E beta MHC class II;MHC class II;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor Violet 450 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P14483 O78196
Gene ID:14961,14969
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:These class II molecules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2b,d,q,r bearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins.

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