The GenieFluor Violet 450 Anti-Mouse Ly6G Antibody (1A8) from Assay Genie (AGEL2977) is a highly specific tool designed for researchers working with mouse models to investigate Ly6G, a glycoprotein expressed on the surface of myeloid cells including neutrophils.This antibody, produced for the detection of Ly6G in mouse samples, is raised using advanced techniques to ensure high specificity and minimal background interference. Its compatibility with flow cytometry and immunofluorescence techniques enables precise visualization and quantification of Ly6G-expressing cells, essential for a wide range of studies in immunology, inflammation, and infection research.
Ly6G is a well-known marker for neutrophils, a critical component of the innate immune system involved in defending the host against pathogens. By targeting Ly6G, researchers can gain valuable insights into neutrophil function, migration, and activation in various disease models including infection, autoimmunity, and cancer.With its reliability, sensitivity, and specificity, the GenieFluor Violet 450 Anti-Mouse Ly6G Antibody (1A8) is a valuable tool for unraveling the complex roles of neutrophils in immune responses and disease pathogenesis, offering new avenues for therapeutic development and advancing our understanding of immune-mediated processes.
Genie Fluor Violet 450 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie FluorViolet 450
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P35461
Gene ID:
546644
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Lymphocyte antigen 6 complex, locus G (Ly-6G), a 21-25 kD GPI-anchored protein, is expressed on the majority of myeloid cells in bone marrow and peripheral granulocytes.