The GenieFluor Violet 450 Anti-Mouse Ly-6G/Ly-6C (GR-1) Antibody (RB6-8C5) - AGEL2985 is a cutting-edge tool for researchers studying immune cells in mouse models. This highly specific antibody targets the Ly-6G/Ly-6C (GR-1) protein, a key marker for myeloid-derived suppressor cells (MDSCs) and granulocytes in mice.MDSCs and granulocytes are essential components of the immune system with implications in cancer, inflammation, and infection. The RB6-8C5 antibody, optimized for use in flow cytometry and immunofluorescence, allows for precise identification and characterization of these cell populations in research settings. Its superb reactivity and validation guarantee reliable results, aiding in the understanding of immune responses and disease pathogenesis in mouse models.
With its ability to detect Ly-6G/Ly-6C (GR-1) protein, the RB6-8C5 antibody is a valuable asset in immunology research, offering insights into immune cell dynamics and function. Researchers investigating cancer immunology, inflammatory diseases, and immune modulation will find this antibody indispensable for their studies. Explore the potential of immune cell targeting and manipulation with the GenieFluor Violet 450 Anti-Mouse Ly-6G/Ly-6C (GR-1) Antibody (RB6-8C5) - AGEL2985.
Genie Fluor Violet 450 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
Genie FluorViolet 450
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P35461 P0CW03
Gene ID:
546644 ,17067
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.