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GenieFluor Violet 450 Anti-Mouse IL-17A Antibody [17F3] (AGEL3129)

SKU:
AGEL3129
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
ICFCM
Reactivity:
Mouse
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
17F3
Conjugation:
AFViolet 450
€229 - €539
Frequently bought together:

Description

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GenieFluor Violet 450 Anti-Mouse IL-17A Antibody [17F3]

The GenieFluor Violet 450 Anti-Mouse IL-17A Antibody (17F3) is a powerful tool for researchers studying IL-17A, a cytokine involved in inflammatory responses and autoimmune diseases. This antibody, developed by Assay Genie, is specifically designed to target mouse IL-17A and is ideal for use in flow cytometry and immunofluorescence applications.IL-17A is a key mediator of inflammation and has been implicated in various autoimmune conditions such as rheumatoid arthritis and inflammatory bowel disease. By targeting IL-17A, researchers can gain valuable insights into the role of this cytokine in disease pathology and potential therapeutic interventions.

The GenieFluor Violet 450 Anti-Mouse IL-17A Antibody (17F3) offers high specificity and sensitivity, enabling accurate detection and quantification of mouse IL-17A in complex biological samples. Its bright violet fluorescence ensures clear and reliable results, making it a valuable tool for immunology and inflammation research.Researchers looking to investigate the function of IL-17A in mouse models or explore potential therapeutic strategies targeting this cytokine will find the GenieFluor Violet 450 Anti-Mouse IL-17A Antibody (17F3) an indispensable resource for their studies.

Product Title:GenieFluor Violet 450 Anti-Mouse IL-17A Antibody [17F3]
SKU:AGEL3129
Size:25µg, 100µg
Clone No:17F3
Synonyms:Interleukin-17A;Il17a;Ctla8;
Host Species:Mouse
Reactivity:Mouse
Application:ICFCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor Violet 450 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q62386
Gene ID:16171
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-49A in vivo.

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