The GenieFluor Violet 450 Anti-Mouse H-2 Antibody (M1/42) is a highly specific monoclonal antibody designed for use in immunology research. This antibody targets the H-2 antigen expressed on mouse cells, allowing for precise detection and analysis in various experimental applications.The H-2 antigen, a major histocompatibility complex (MHC) molecule, plays a crucial role in antigen presentation and immune response regulation in mice. By targeting this specific antigen, researchers can gain valuable insights into the immune system function, including T-cell activation, antigen recognition, and immune surveillance mechanisms.The GenieFluor Violet 450 Anti-Mouse H-2 Antibody (M1/42) offers exceptional sensitivity and specificity, making it an essential tool for studies involving mouse models of immunological diseases, transplantation, infectious diseases, and vaccine development.
Its compatibility with flow cytometry, immunofluorescence, and other molecular biology techniques makes it versatile for a wide range of research applications.With its high-quality performance and reliability, this antibody is a valuable asset for scientists and researchers striving to unravel the complexities of the immune system and advance our understanding of immune-mediated diseases.
Mouse major histocompatibility complex (MHC) H-2; MHC I;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
Genie Fluor Violet 450 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie FluorViolet 450
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Gene ID:
111364
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
The M1/42 antibody reacts with the H-2 MHC class I alloantigens expressed on nucleated cells from mice of the a, b, d, j, k, s, and u haplotypes (Stallcup, KC et al, 1981). MHC class I is involved in antigen presentation to T cells expressing CD3/TCR and CD8 proteins.