The GenieFluor Violet 450 Anti-Mouse H-2 Antibody (M1/42) is a highly specific monoclonal antibody designed for research involving mouse H-2 antigens. H-2 antigens are major histocompatibility complex (MHC) molecules essential for antigen presentation and immune response regulation in mice. The M1/42 antibody, with its exquisite specificity for mouse H-2 molecules, is a valuable tool for immunology research, particularly in studies related to antigen presentation, T cell activation, and immune system function in mouse models.This antibody is ideal for applications such as flow cytometry, immunofluorescence, and immunohistochemistry, allowing researchers to precisely visualize and analyze H-2 antigen expression in various mouse tissues and cells. Its high sensitivity and specificity make it a reliable reagent for investigating immune responses, immune cell activation, and antigen recognition in mouse models of disease.
By targeting mouse H-2 antigens, the GenieFluor Violet 450 Anti-Mouse H-2 Antibody (M1/42) provides researchers with a powerful tool to deepen their understanding of immune responses and antigen presentation mechanisms in mouse models. Its reliability and specificity make it an indispensable resource for studies exploring the intricate interactions between MHC molecules and immune cells in various research fields, including immunology, infectious diseases, and autoimmunity.Discover new insights into mouse immune system dynamics and antigen presentation processes with the GenieFluor Violet 450 Anti-Mouse H-2 Antibody (M1/42), a trusted tool for precise and reliable immunological research in mouse models.
Mouse major histocompatibility complex (MHC) H-2; MHC I;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
Genie Fluor Violet 450 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie FluorViolet 450
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Gene ID:
111364
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
The M1/42 antibody reacts with the H-2 MHC class I alloantigens expressed on nucleated cells from mice of the a, b, d, j, k, s, and u haplotypes (Stallcup, KC et al, 1981). MHC class I is involved in antigen presentation to T cells expressing CD3/TCR and CD8 proteins.