The GenieFluorâ„¢ Violet 450 Anti-Mouse CD90.2 Antibody (30H12) is a cutting-edge tool for researchers studying mouse CD90.2, a cell surface marker commonly used to identify mouse T cells, hematopoietic stem cells, and thymocytes. This antibody, specifically targeting mouse CD90.2, is developed using innovative technology to ensure high specificity and sensitivity in various experimental applications. Validated for flow cytometry, immunofluorescence, and immunohistochemistry, the GenieFluorâ„¢ Violet 450 Anti-Mouse CD90.
2 Antibody (30H12) offers reliable detection and visualization of CD90.2 expression in mouse cells. Researchers can confidently utilize this antibody to explore the role of CD90.2 in immune cell differentiation, activation, and function, leading to valuable insights in immunology, stem cell research, and disease models.
Genie Fluor Violet 450 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
Genie FluorViolet 450
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Gene ID:
21838
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.