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GenieFluor Violet 450 Anti-Mouse CD8a Antibody [53-6.7] (AGEL2972)

SKU:
AGEL2972
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, κ
Clone:
53-6.7
Conjugation:
AFViolet 450
€109 - €249
Frequently bought together:

Description

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GenieFluor Violet 450 Anti-Mouse CD8a Antibody [53-6.7]

The GenieFluor Violet 450 Anti-Mouse CD8a Antibody (53-6.7) is a powerful tool for immunology research, specifically targeting the CD8a protein on mouse cells. This antibody, identified as AGEL2972, is optimized for fluorescence detection at 450 nm, delivering accurate and reliable results for flow cytometry and immunofluorescence applications.The CD8a protein is a crucial marker for identifying cytotoxic T cells, a key player in the adaptive immune response. By targeting and binding to CD8a, this antibody allows for the precise detection and analysis of CD8a-expressing cells in various experimental settings.

Its high specificity and sensitivity make it an excellent choice for researchers studying T cell biology, immune responses, and immunotherapies in mouse models.With its superior performance in fluorescence-based techniques, the GenieFluor Violet 450 Anti-Mouse CD8a Antibody (53-6.7) provides researchers with a valuable tool for investigating immune cell populations, monitoring immune responses, and unraveling the complexities of the immune system. Trust in this antibody to enhance your research and drive new discoveries in the field of immunology.

Product Title:GenieFluor Violet 450 Anti-Mouse CD8a Antibody [53-6.7]
SKU:AGEL2972
Size:50 Tests, 100 Tests, 200 Tests
Clone No:53-6.7
Synonyms:T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor Violet 450 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P01731
Gene ID:12525
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.

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