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GenieFluor Violet 450 Anti-Mouse CD80 Antibody [16-10A1] (AGEL2945)

SKU:
AGEL2945
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
Armenian Hamster IgG
Clone:
16-10A1
Conjugation:
AFViolet 450
$275
Frequently bought together:

Description

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GenieFluor Violet 450 Anti-Mouse CD80 Antibody [16-10A1]

The GenieFluor Violet 450 Anti-Mouse CD80 Antibody (16-10A1) is a cutting-edge tool for researchers studying immune responses and cell surface markers in mice. This antibody, raised against CD80, a co-stimulatory molecule involved in T cell activation, is specifically designed for flow cytometry applications. With high reactivity towards mouse samples, it enables precise detection and analysis of CD80 expression in various cell populations.CD80, also known as B7-1, is a crucial regulator of T cell activation and immune responses. Its interactions with CD28 on T cells play a pivotal role in initiating immune reactions. By targeting CD80, researchers can delve deeper into the mechanisms underlying T cell activation, immune regulation, and autoimmune diseases.

This antibody provides a reliable tool for investigating the role of CD80 in modulating immune responses and designing therapeutic strategies targeting this pathway.Whether studying immune cell interactions, autoimmune diseases, or vaccine development, the GenieFluor Violet 450 Anti-Mouse CD80 Antibody (16-10A1) offers a versatile solution for precise and reliable detection of CD80 expression in mouse models. Explore the intricate world of immune regulation and T cell co-stimulation with this advanced antibody.

Product Title:GenieFluor Violet 450 Anti-Mouse CD80 Antibody [16-10A1]
SKU:AGEL2945
Size:25µg, 100µg
Clone No:16-10A1
Synonyms:T-lymphocyte activation antigen CD80;Cd80;Activation B7-1 antigen;B7;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:Genie Fluor Violet 450 Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q00609
Gene ID:12519
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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