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GenieFluor Violet 450 Anti-Mouse CD80 Antibody [16-10A1] (AGEL2944)

SKU:
AGEL2944
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
Armenian Hamster IgG
Clone:
16-10A1
Conjugation:
AFViolet 450
$299 - $683

Description

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GenieFluor Violet 450 Anti-Mouse CD80 Antibody [16-10A1]

The GenieFluor Violet 450 Anti-Mouse CD80 Antibody (16-10A1) from AssayGenie (AGEL2944) is a cutting-edge tool for immunological research, particularly in the study of immune cell activation and co-stimulatory pathways. This monoclonal antibody specifically targets mouse CD80, a vital cell surface molecule involved in T cell activation and immune response regulation.Engineered for high sensitivity and specificity, the GenieFluor Violet 450 Anti-Mouse CD80 Antibody (16-10A1) is ideal for flow cytometry and immunofluorescence applications, enabling precise detection and quantification of CD80 expression on mouse immune cells. Its superior performance in these assays makes it an invaluable asset for researchers exploring immune system dynamics, host-pathogen interactions, and autoimmune diseases in murine models.

By targeting CD80, a key player in immune modulation and antigen presentation, this antibody opens up new possibilities for investigating the intricate mechanisms underlying immune activation and tolerance. Whether studying immune checkpoint pathways, vaccine development, or autoimmune disorders, the GenieFluor Violet 450 Anti-Mouse CD80 Antibody (16-10A1) provides researchers with a trusted tool to uncover crucial insights into the complex world of immune regulation.

Product Title:GenieFluor Violet 450 Anti-Mouse CD80 Antibody [16-10A1]
SKU:AGEL2944
Size:50 Tests, 100 Tests, 200 Tests
Clone No:16-10A1
Synonyms:T-lymphocyte activation antigen CD80;Cd80;Activation B7-1 antigen;B7;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:Genie Fluor Violet 450 Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q00609
Gene ID:12519
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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