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GenieFluor Violet 450 Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219] (AGEL3243)

SKU:
AGEL3243
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, k
Clone:
R17 217.1.3/TIB-219
Conjugation:
AFViolet 450
€229 - €549
Frequently bought together:

Description

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GenieFluor Violet 450 Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219]

The GenieFluor Violet 450 Anti-Mouse CD71 Antibody (R17-217.1.3) Tib-219 (AGEL3243) is a powerful tool designed for researchers working with mouse samples to study CD71, a cell surface marker associated with iron metabolism and erythroid development. This antibody, optimized for use in flow cytometry and immunofluorescence applications, specifically targets CD71, allowing for precise detection and analysis in a variety of experimental settings.CD71, also known as transferrin receptor protein 1, plays a vital role in cellular iron uptake and is particularly important in erythroid cells for hemoglobin synthesis. By targeting CD71, researchers can gain insights into the regulation of iron homeostasis, erythropoiesis, and related physiological processes.

This antibody’s high specificity and sensitivity make it an invaluable tool for investigations in areas such as hematopoiesis, iron metabolism disorders, and cancer research involving tumor cell proliferation and iron utilization.With its ability to target CD71 in mouse samples, the GenieFluor Violet 450 Anti-Mouse CD71 Antibody (R17-217.1.3) Tib-219 (AGEL3243) offers researchers a reliable solution for studying the intricate mechanisms associated with iron metabolism and erythroid development in various biological contexts.

Product Title:GenieFluor Violet 450 Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219]
SKU:AGEL3243
Size:25µg, 100µg
Clone No:R17 217.1.3/TIB-219
Synonyms:Transferrin receptor protein 1;Tfrc;TR;TfR;TfR1;Trfr;CD71;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor Violet 450 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q62351
Gene ID:22042
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD71 is a 95 kD type II heterodimeric transmembrane glycoprotein that is also known as T9 and transferrin receptor. CD71 is expressed on proliferating cells, reticulocytes, and erythroid precursors. Its expression is very low on resting leukocytes. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.

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