The GenieFluor Violet 450 Anti-Mouse CD5 Antibody (53-7.3) is a cutting-edge tool for researchers studying CD5, a crucial cell surface marker involved in immune response and regulation. This antibody, tailored for mouse samples, offers high specificity and sensitivity in various experimental applications, including flow cytometry and immunofluorescence imaging. By targeting the CD5 protein, this antibody enables precise detection and characterization of CD5-expressing cells in research related to immunology, autoimmune diseases, and lymphocyte development.
CD5, a well-known marker on T and B lymphocytes, plays a pivotal role in modulating immune cell activation and tolerance. Its involvement in signaling pathways and immune cell interactions underscores its significance in understanding immune responses in health and disease contexts. The GenieFluor Violet 450 Anti-Mouse CD5 Antibody provides researchers with a valuable tool to delve into the functional aspects of CD5 expression and its impact on immune system dynamics, presenting opportunities for novel therapeutic strategies in immune-related disorders.
Genie Fluor Violet 450 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie FluorViolet 450
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P13379
Gene ID:
12507
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD5 is a 67 kD protein, also known as Lyt-1, Ly-1, T1, Tp67, or Ly-12. It is a member of the scavenger receptor cysteine-rich protein superfamily (SRCR) and primarily expressed on thymocytes, T cells, and B-1 cells. Although mature α/β T cells express high levels of CD5, very few γ/δ T cells express this antigen. The interaction of CD5 with CD72, gp35-37, TCR, or BCR is involved in T and B cell activation.