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GenieFluor Violet 450 Anti-Mouse CD49b Antibody [DX5] (AGEL3258)

SKU:
AGEL3258
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgM, k
Clone:
DX5
Conjugation:
AFViolet 450
€209 - €429

Description

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GenieFluor Violet 450 Anti-Mouse CD49b Antibody [DX5]

The GenieFluor Violet 450 Anti-Mouse CD49b Antibody (DX5) is a powerful tool for researchers studying immune cells expressing CD49b, a marker associated with natural killer cells and other subsets of lymphocytes. This antibody is specifically designed for use in flow cytometry and immunofluorescence applications, providing reliable and sensitive detection of CD49b-expressing cells in mouse samples.CD49b, also known as DX5, is a key marker for identifying natural killer cells in mice, playing a crucial role in immune responses to pathogens and tumor surveillance. By targeting CD49b, researchers can analyze the presence and function of these important immune cells in various experimental models, offering insights into immune system activation, regulation, and dysfunction.

The GenieFluor Violet 450 Anti-Mouse CD49b Antibody (DX5) offers high specificity and sensitivity, enabling precise identification and quantification of CD49b-expressing cells in immunological studies. With its reliable performance, this antibody is a valuable asset for research in immunology, cancer biology, and other fields where understanding natural killer cell function is essential.

Product Title:GenieFluor Violet 450 Anti-Mouse CD49b Antibody [DX5]
SKU:AGEL3258
Size:25µg, 100µg
Clone No:DX5
Synonyms:Integrin alpha-2;CD49 antigen-like family member B;Collagen receptor;Platelet membrane glycoprotein Ia;GPIa;VLA-2 subunit alpha;CD49b;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Isotype Control:Genie Fluor Violet 450 Rat IgM, κ Isotype Control[RTK2118]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q62469
Gene ID:16398
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

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