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GenieFluor Violet 450 Anti-Mouse CD49b Antibody [DX5] (AGEL3256)

SKU:
AGEL3256
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgM, k
Clone:
DX5
Conjugation:
AFViolet 450
€159 - €389
Frequently bought together:

Description

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GenieFluor Violet 450 Anti-Mouse CD49b Antibody [DX5]

The GenieFluor Violet 450 Anti-Mouse CD49b Antibody (DX5) (AGEL3256) is a powerful tool for researchers studying immune cells in mice. This antibody is specifically designed to target CD49b, a cell surface marker commonly used to identify natural killer cells in murine models.Utilizing cutting-edge technology, this antibody offers high specificity and sensitivity in detecting CD49b-expressing cells in various tissues and experimental conditions. Its bright violet fluorescence allows for accurate visualization and analysis of these immune cells, making it an excellent choice for flow cytometry and immunofluorescence applications.CD49b is a key molecule involved in the activation and function of natural killer cells, which play a crucial role in the immune response against infections and tumors.

By targeting CD49b with this antibody, researchers can gain valuable insights into the behavior and function of natural killer cells in different disease models, immunotherapy studies, and investigations into immune responses.Overall, the GenieFluor Violet 450 Anti-Mouse CD49b Antibody (DX5) (AGEL3256) is a reliable reagent that facilitates detailed characterization and quantification of CD49b-positive cells, enhancing understanding in the fields of immunology, cancer research, and immunotherapy development.

Product Title:GenieFluor Violet 450 Anti-Mouse CD49b Antibody [DX5]
SKU:AGEL3256
Size:50 Tests, 100 Tests, 200 Tests
Clone No:DX5
Synonyms:Integrin alpha-2;CD49 antigen-like family member B;Collagen receptor;Platelet membrane glycoprotein Ia;GPIa;VLA-2 subunit alpha;CD49b;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Isotype Control:Genie Fluor Violet 450 Rat IgM, κ Isotype Control[RTK2118]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q62469
Gene ID:16398
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

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