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GenieFluor Violet 450 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1] (AGEL2983)

SKU:
AGEL2983
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgM, κ
Clone:
RA3.3A 1/6.1
Conjugation:
AFViolet 450
€189 - €429
Frequently bought together:

Description

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GenieFluor Violet 450 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]

The GenieFluor Violet 450 Anti-Mouse CD45R (B220) Antibody (RA3-6B2) is a crucial tool for researchers studying mouse immune cells, particularly B lymphocytes. This antibody, validated for flow cytometry and other immunological applications, specifically targets the CD45R (B220) protein found on the surface of B cells. By binding to CD45R (B220), researchers can accurately identify and analyze B cell populations in various mouse samples.CD45R (B220) is a well-known marker for B lymphocytes and plays a pivotal role in immune responses. Its expression is primarily restricted to B cells, making it a reliable identifier for these specialized cells within the immune system.

Understanding the distribution and function of B cells in different experimental settings is essential for advancing knowledge in immunology, vaccine development, and autoimmune disease research.The GenieFluor Violet 450 Anti-Mouse CD45R (B220) Antibody (RA3-6B2) provides researchers with a high-quality, reliable tool for investigating B cell populations in mouse models. Its specificity and sensitivity make it an excellent choice for experiments requiring precise identification and characterization of B lymphocytes, furthering the understanding of immune responses in health and disease.

Product Title:GenieFluor Violet 450 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]
SKU:AGEL2983
Size:25µg, 100µg
Clone No:RA3.3A 1/6.1
Synonyms:B220;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Isotype Control:Genie Fluor Violet 450 Rat IgM, κ Isotype Control[RTK2118]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Gene ID:19264,5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.

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