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GenieFluor Violet 450 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1] (AGEL2981)

SKU:
AGEL2981
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgM, κ
Clone:
RA3.3A 1/6.1
Conjugation:
AFViolet 450
€159
Frequently bought together:

Description

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GenieFluor Violet 450 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]

The GenieFluor Violet 450 Anti-Mouse CD45R (B220) Antibody (RA3-6B2) from Assay Genie (product code: AGEL2981) is a highly specific antibody designed for research applications involving mouse CD45R, also known as B220. CD45R is a cell surface marker predominantly expressed on B cells and a subset of T cells.This antibody, raised against mouse samples, has been rigorously validated for use in various experimental techniques such as flow cytometry and immunohistochemistry. It demonstrates excellent sensitivity and specificity in detecting the CD45R antigen, enabling precise identification and analysis of B cells in mouse models. Mouse CD45R (B220) is a crucial marker for identifying B cell populations and studying their functions in immune responses, autoimmune diseases, and B cell malignancies.

By targeting CD45R with this antibody, researchers can gain valuable insights into the role of B cells in immune regulation, lymphocyte development, and antibody production.Overall, the GenieFluor Violet 450 Anti-Mouse CD45R (B220) Antibody (RA3-6B2) from Assay Genie is a reliable tool for researchers investigating B cell biology, immunology, and related fields in mouse model systems. Its high specificity and performance make it an essential reagent for studies aimed at understanding the intricate mechanisms underlying immune responses and B cell-mediated diseases.

Product Title:GenieFluor Violet 450 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]
SKU:AGEL2981
Size:50 Tests, 100 Tests, 200 Tests
Clone No:RA3.3A 1/6.1
Synonyms:B220;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Isotype Control:Genie Fluor Violet 450 Rat IgM, κ Isotype Control[RTK2118]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Gene ID:19264,5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.

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