The GenieFluor Violet 450 Anti-Mouse CD45 Antibody (30-F11) is a highly specific and sensitive tool designed for researchers studying mouse CD45, a protein widely used as a pan-leukocyte marker in immunology. This antibody, manufactured by Assay Genie, has been developed to provide precise detection and analysis of CD45 in a variety of mouse cell types.Mouse CD45, also known as leukocyte common antigen, is a key marker for identifying and characterizing immune cells. Its expression pattern and regulation have been linked to various immune and inflammatory processes. The GenieFluor Violet 450 Anti-Mouse CD45 Antibody (30-F11) offers researchers the ability to accurately visualize and quantify CD45 expression, aiding in the understanding of immune cell populations, immune responses, and disease mechanisms in mouse models.
This antibody is ideal for flow cytometry and immunofluorescence applications, providing researchers with a reliable tool to investigate the role of CD45 in immunology, inflammation, infectious diseases, and beyond. With its high specificity and performance in mouse samples, the GenieFluor Violet 450 Anti-Mouse CD45 Antibody (30-F11) is a valuable asset for studies aiming to elucidate the intricate functions of CD45 in the immune system.
Genie Fluor Violet 450 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
Genie FluorViolet 450
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P06800
Gene ID:
19264
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.