The GenieFluor Violet 450 Anti-Mouse CD45 Antibody (30-F11) from Assay Genie (AGEL2993) is a cutting-edge tool for researchers studying mouse immune cells. This antibody specifically targets CD45, a critical marker for identifying various immune cell populations in mice. Through its highly selective binding to CD45, this antibody allows for precise detection and analysis of mouse immune cells in research applications such as flow cytometry and immunofluorescence. Its superior performance and specificity make it an invaluable reagent for studying immune cell populations in mouse models, enabling researchers to gain deeper insights into immune responses, inflammation, and disease progression.
With its high reactivity and validation for use in a wide range of experimental techniques, the GenieFluor Violet 450 Anti-Mouse CD45 Antibody (30-F11) is a must-have tool for immunologists, cancer researchers, and anyone investigating immune cell function in mouse models. Explore new possibilities in your research with this advanced antibody from Assay Genie.
Genie Fluor Violet 450 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
Genie FluorViolet 450
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P06800
Gene ID:
19264
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.