The GenieFluor Violet 450 Anti-Mouse CD45.1 Antibody (A20) (AGEL3072) is a cutting-edge immunological tool designed for precise research applications involving the mouse CD45.1 antigen. This antibody, utilizing the advanced GenieFluor Violet 450 fluorophore, offers exceptional sensitivity and specificity in detecting CD45.1 expression in mouse samples.CD45.1, a glycoprotein found on the surface of immune cells, is known for its pivotal role in immune cell activation and signaling. The anti-CD45.1 antibody (A20) is meticulously developed to efficiently bind to the CD45.1 protein, facilitating accurate detection and analysis in a variety of cell types and experimental settings. It is a valuable asset for researchers investigating immune cell populations, immune responses, and cell signaling pathways in both basic research and disease models.
Ideal for use in flow cytometry, immunofluorescence, and other immunological techniques, this anti-mouse CD45.1 antibody enables researchers to explore and characterize immune cell subsets and their functions with high precision and reliability. With its exceptional performance and specificity, the GenieFluor Violet 450 Anti-Mouse CD45.1 Antibody (A20) (AGEL3072) is a valuable tool for immunologists, cell biologists, and researchers studying immune-mediated diseases and immune system function in mouse models.Discover new insights and enhance your research capabilities with the GenieFluor Violet 450 Anti-Mouse CD45.1 Antibody (A20) (AGEL3072) from AssayGenie - your partner in cutting-edge immunological tools.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Gene ID:
19264
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD45.1 is an alloantigen of CD45, expressed by Ly5.1 bearing mouse strains (e.g., RIII, SJL/J, STS/A, DA). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in mice that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell types. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.