The GenieFluor Violet 450 Anti-Mouse CD4 Antibody (GK1.5) is a powerful tool for researchers studying immune responses in mice. This antibody, validated for use in flow cytometry and immunofluorescence applications, specifically targets the CD4 protein on the surface of mouse T-cells.CD4 is a crucial marker for T-helper cells, which play a central role in coordinating the immune response. By specifically binding to CD4, the GK1.5 antibody allows for the identification and analysis of CD4-positive T-cells in various mouse models.
This makes it an invaluable tool for studying immune regulation, inflammation, and autoimmune diseases in preclinical research settings.With its high reactivity and specificity, the GenieFluor Violet 450 Anti-Mouse CD4 Antibody (GK1.5) is a reliable reagent for investigating the role of CD4-positive T-cells in immune responses and disease pathogenesis in mouse models. Its versatility and performance make it an essential component of any immunology research toolkit.
Genie Fluor Violet 450 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
Genie FluorViolet 450
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P06332
Gene ID:
12504
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosin kinase, lck.