The GenieFluor Violet 450 Anti-Mouse CD3 Antibody (17A2) is a cutting-edge tool designed for researchers working with mouse models to study CD3 expression and T cell biology. This antibody is specifically engineered to target CD3, a key cell surface marker found on T cells, enabling precise detection and analysis in various experimental settings.With its high specificity and sensitivity, this antibody is ideal for use in flow cytometry, immunofluorescence, and other immunological techniques to study T cell development, activation, and function.
The GenieFluor Violet 450 Anti-Mouse CD3 Antibody (17A2) opens up new possibilities for investigating immune responses, autoimmune diseases, and therapeutic interventions in preclinical research. Its reliable performance and versatility make it an essential tool for advancing our understanding of T cell biology and immunology.
T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
Genie Fluor Violet 450 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
Genie FluorViolet 450
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P04235 P11942 P22646 P24161
Gene ID:
12502
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.