The GenieFluor Violet 450 Anti-Mouse CD3 Antibody (145-2C11) from AssayGenie (AGEL3251) is a cutting-edge tool for researchers working with mouse models in immunology and cancer research. This antibody is specifically designed to target the CD3 protein on mouse T cells, allowing for precise detection and analysis in a variety of experimental settings.The CD3 protein is a key component of the T cell receptor complex and plays a crucial role in T cell activation and function. By utilizing the GenieFluor Violet 450 Anti-Mouse CD3 Antibody, researchers can effectively monitor T cell responses, investigate immune cell behavior, and study the impact of various treatments on T cell activity.
With its high specificity and sensitivity, this antibody provides reliable results in flow cytometry, immunofluorescence, and other experimental techniques. Its compatibility with mouse samples ensures accurate and reproducible data for studies on T cell biology, immunotherapy, and autoimmune diseases.Overall, the GenieFluor Violet 450 Anti-Mouse CD3 Antibody (145-2C11) is a valuable resource for researchers seeking to deepen their understanding of T cell dynamics and develop innovative approaches to combat immune-related disorders.
Genie Fluor Violet 450 Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
Genie FluorViolet 450
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P22646
Gene ID:
12501
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.